TACA-16 自闭症中言语问题的医学原因
本帖最后由 StarCare 于 2026-5-15 16:20 编辑TACA-16 自闭症中言语问题的医学原因
Medical Causes of Speech Issues in Autism
原文网址：https://tacanow.org/family-resou ... h-issues-in-autism/
概述
言语是一种复杂功能，需要多个大脑区域和身体系统协同工作。因此，言语问题可以有多种原因。好消息是，识别和治疗这些潜在医学问题可以改善言语能力。本文将讨论自闭症中言语问题的常见医学原因。
Medical Causes of Speech
Issues in Autism
自闭症中言语问题的病因
All contents of this resource were created for informational purposes only and are not intended to be a
substitute for professional advice, diagnosis, or treatment. Always seek the advice of your physician,
therapist, or other qualified health providers with any questions or concerns you may have.
本资源的所有内容仪出于信息目的而创建，并不旨在蔡代专业建议、诊断或治疗。如有任何疑问或顾虑，请务必咨询
您的医生、治疗师或其他合格的医疗保健提供者。
@OO
This article provides information about medical causes for speech issues in autism as well as treatment
options.
本文提供了有关自闭症中言语问题以及治疗方案的医学原因的信息。
Please note: There are two approaches to addressing speech issues in autism: medical and therapeutic.
TACA recommends that parents seek to address speech issues from both approaches to achieve the
best possible outcome for their child.
请注意: 解决自闭症言语问题的方法有两种: 医学方法和治疗方法。TACA 建议家长采用这两种方法来解决言语
问题，以实现对孩子最好的治疗效果。
To learn more about the therapeutic approach, read Therapeutic and Communication Options for
Speech Issues in Autism”.
要详细了解治疗方法，请阅读“自闭症言语问题的治疗和沟通方法"。
A
Medical Issues That Cause or Contribute to
Speech Issues in Autism
导致或加重自闭症言语问题的医学问题
Underlying medical conditions can cause or exacerbate Speech issues in autism. Below you will find a
brief description of some of these medical issues to discuss with your child’s physician. A good functional
medicine practitioner, who is familiar with treating medical conditions common to autism, can help you on
this journey.
潜在的医学状况会导致或加重自闭症的言语问题。以下是对其中一些医学问题的简要说明，您可以与孩子的医生
讨论。一位优秀的医学功能从业者 (熟悉治疗自闭症常见医学状况) 可以帮助您解决这个问题。
Seizures fmmARIE
When determining if a medical condition causing or contributing to your child’s speech issues, it is
important to evaluate for seizures. Seizure activity that occurs in the area of the brain that supports
speech and language, will cause your child will experience communication difficulties.
TRESHAMNBAT Sian S VOR, PHomAArR REE, ATT ARSUS SIS Ke
发作活动会导致孩子出现交流困难。
Also, it is important for parents to understand that seizures are common to autism. In fact, it is estimated
that up to 45% of individuals with ASD are affected by seizures by the time they reach adulthood, and up
to 60% ha
Sh, LET RRASA ANS MEK RES, Bt, fehit, Sik 45% 的 ASD SAE RENSS SM
病的影响，多达 60% HRASHWE mA a_i Ss BAILA HAA SATII ACLE
Unfortunately, seizures often go undiagnosed in individuals with autism. This happens for several
reasons, but mainly because the symptoms of seizures mimic symptoms that we typically associate with
autism, such as stimming, sleep issues, and motor tics.
ASNE, MNTEAAESS PSSA KALNRA, (FBSA AMRIT SERS
自闭症相关的症状，例如刻板行为、睡孔问题和运动抽动症。
Seizures may also be missed during the initial evaluation process. This can occur if your child’s
neurologist relies solely on the results of a 30-minute EEG when checking for seizure activity. For
example, unless your child happens to have a seizure during the 30-minute period they are hooked up to
the EEG equipment, the doctor is likely to conclude that seizures aren't an issue. But, what if your child
only has seizures while they’re sleeping? For this reason, we recommend that every child with autism
have at least a 24-hour EEG.
APA HAER ORS. MRCNAFNREE NE SAT RR 30 分钟脑电图的结果，则可
能会发生这种情况。例如，除非您的孩子在连接脑电图设备的 30 分钟内恰好疗病发作，否则医生可能会得出结
it, BARS, (22, UPENRTRACB RNA SAREE? 因此，我们建议每个自闭症儿童至少进
行一次 24 小时脑电图检查。
You can read more about seizures here.
Co EAN ANS Sie.
Mitochondrial Dysfunction
线粒体功能障碍
Another medical condition, common to autism, that can cause Speech issues is mitochondrial
dysfunction. The prevalence of mitochondrial dysfunction among individuals with autism is high. To
demonstrate, current research suggests it may be present in up to 80% of children with autism.
另一种常见的自闭症医学病症可能会导致言语问题，即线粒体功能障碍。自闭症患者中线粒体功能障碍的患病率
很高。举例来说，目前的研究表明，多达 80% 的自闭症儿童可能存在这种病症。
Symptoms of mitochondrial dysfunction vary. They include, but are not limited to, GI distress, headaches,
fatigue, clumsiness, slow cognitive performance, slow processing speed, developmental delay or delay in
growth, seizures, and more. However, you can alleviate many of these symptoms with a mitochondrial
cocktail given at proper doses.
线粒体功能障碍的症状各不相同。它们包括但不限于胃肠道不适、头痛、疲劳、笨拙、认知表现迟缓、处理速度
慢、发育迟缓或生长迟缓、癖冯发作等。但是，您可以通过适当剂量的线粒体鸡尾酒来缓解其中许多症状。
Click here to learn more about mitochondrial dysfunction.
点击此处以详细了解线粒体功能障碍。
Learn about lab testing for mitochondrial dysfunction here.
在此处了解线粒体功能障碍的实验室检测。
Cerebral Folate Deficiency (CFD)
脑叶酸缺乏症 (CFD)
Cerebral Folate Deficiency (CFD) can also cause or contribute to speech issues in autism. This is a
relatively newly identified disorder in which there is low 5-MTHF (5-methyltetrahydrofolate) in the
cerebrospinal fluid, but normal, or even elevated 5-MTHF, in the blood. In other words, the brain doesn't
have enough folate to function properly.
脑叶酸缺乏症 (CFD) 也会导致或加剧自闭症的言语问题。这是一种相对新近发现的疾病，其特征是脑状液中 5-
MTHF (5-甲基四氢叶酸) 含量低，而血液中 5-MTHF 含量正常甚至升高。换句话说，大脑没有足够的叶酸来正
常发挥功能。
Symptoms of CFD include developmental delays, speech difficulties, sleep issues, irritability, and more.
Treatment options include prescription medications (Leucovorin, Deplin, or both) and the elimination of
dairy from the diet because mammal milk blocks folate receptors.
CFD 的症状包括发育迟缓、言语困难、睡眠问题、易她等。治疗方案包括处方药 (亚叶酸、地普林或两者兼有)
和从饮食中去除乳制品，因为哺乳动物的乳汁会阻断叶酸受体。
Click here to learn more about Cerebral Folate Deficiency.
点击此处以详细了解脑叶酸缺乏症。
Vitamin and Nutrient Deficiencies
维生素和营养素缺乏
The body needs sufficient amounts of specific vitamins and nutrients to perform certain functions.
Speech is no exception to this rule. The good news is that, oftentimes, vitamin and nutrient deficiencies
are easy to address.
身体需要足量的特定维生素和营养素来执行某些功能。言语也不例外。好消息是，维生素和营养素缺乏症通常很
容易解决。
Read this TACA article on Nutritional Deficiences in Autism to learn more.
Medical Causes of Speech Issues in Autism:
Nutritional and Dietary Treatment Options
自闭症言语问题的病因: 营养和饮食治疗方案
Nutritional and dietary interventions can alleviate many underlying medical problems that cause Speech
issues in autism. Below you will find a list of treatment options to discuss with your child’s functional
medicine doctor.
BF ARA TA eit Ss SMAAES Baan eee Sah, CSE hRE—-NaAPARWR, TS
孩子的功能医学医生讨论。
Gluten Free Casein Free (GFCF) Diet
FsRRFCHRSA (GFCF) 饮食
One of the easiest options for treating several medical problems that cause speech issues in autism is to
modify your child's diet. In fact, for over twenty years parents and clinicians have been reporting that the
gluten-free, casein-free (GFCF) diet is the most beneficial intervention speech. Years ago, they were
ridiculed for saying this, but that is no longer the case. This is because, today, you will find many studies
治疗自闭症中导致言语问题的几种医疗问题最简单的方法之一就是改变孩子的饮食。事实上，二十多年来，家长
和临床医生一直在报告说无秦质、无酷蛋白 (GFCF) 饮食是对言语最有利的干预措施。几年前，他们因说出这名
话而遭到嘲笑，但现在情况已不再如此。这是因为，如今，您会发现许多研究不仅葡持这些临床经验，而且解炎
了它们背后的科学原理。
To clarify, the GFCF diet is merely a change of food. It is not invasive or dangerous. Furthermore,
research shows it can help with cognition, sleep, focus, anxiety, behavior, and gastrointestinal issues in
addition to speech. All things considered, if you can do something at home that is safe and may help your
child, it is always worth a try.
澄清一下，GFCF 饮食仅仅是食物的变化。它不是侵入性的或危险的。此外，研究表明，除了言语之外，它还有
助于认知、睡眠、注意力、焦虑、行为和骨肠道问题。综合考虑所有因素，如果您能在家中做一些安全的事情来
帮助您的孩子，那么总是值得一试。
Find more information about the GFCF diet in the following articles:
在以下文章中查找有关 GFCF 饮食的更多信息:
e Introduction to the Gluten-Free, Casein-Free, Soy-Free Diet
Supplements That Have Been Proven to Help Alleviate Speech Issues in
Autism
已被证明有助于缓解自闭症言语问题的补品
As mentioned above, vitamin and mineral deficiencies can cause or contribute to speech issues in
autism. As a result, your doctor can use nutritional supplementation to address them.
如上所述，维生素和矿物质缺乏会导致或加重自闭症的言语问题。因此，您的医生可以使用莒养补充剂来解决这
些问题。
Below, you will find a list of supplements that scientific research shows can help with speech.
以下列出了科学研究表明有助于言语的补充剂。
Vitamin B12 (Cobalamin) 维生素 B12 (钻胺素)
Vitamin B12 (cobalamin) is an essential vitamin that your body needs for many functions, including
development, cognition, energy, and mood stabilization. Additionally, B12 connects the folate cycle to
the methylation cycle and can be used to treat redox abnormalities.
维生素 B12 (钴胺素) 是人体必需的维生素，具有多种功能，包括发育、认知、能量和情绪稳定。此外，B12 将
叶酸循环与甲基化循环连接起来，可用于治疗氧化还原异常。
。 Study: Effectiveness of methylcobalamin and folinic acid treatment on adaptive behavior in children
研究: 甲钴胺和亚叶酸治疗对自闭症儿童适应性行为的有效性与谷胱甘肽氧化还原状态相关
o Remarkable improvements were seen with B12 and folinic acid treatment (ex: six months of language
improvement in three months!)
使用 B12 和叶酸治疗后，看到了显著的改善 〈例如: 三个月内语言能力提高了六个月! )
e Study: Randomized, Placebo-Controlled Trial of Methyl B12 for Children with Autism
。 Study: Methyl B12 help
in some
在此处阅读有关自闭症的甲基 B12 的更多信息。
Folinic Acid or 5MTHF (Methyltetrahydrofolate)
亚叶酸或 5MTHF (甲基四和氢叶酸)
Alack of 5MTHF causes a functional folate deficiency and even cerebral folate deficiency. This can
cause speech impairment. Accordingly, the supplements, folinic acid and 5MTHF, can address these
SMTHF 的缺乏会导致功能性叶酸缺乏，甚至脑叶酸缺乏。这可能导致言语障碍。因此，补充剂亚叶酸和 SMTHF
可以解决这些缺陷。脑叶酸缺乏需要更高剂量。
It is important to note that folic acid and folinic acid are not the same. Folic acid can block folate
receptors in the brain, making problems worse.
menteils, MAAR RS Els. MARSA ARPANSA, GEARS aS,
研究: 叶酸改善自闭症和语言障碍儿童的语言交流: 一项随机双言安慰剂对照试验
Omega-3 Fatty Acids Omega-3 脂肪酸
Omega-3 fatty acids are a family of essential fatty acids that help with speech and focus. Your body
cannot produce omega-3 fatty acids on its own, so you must get them from your diet.
Omega-3 脂肪酸是一组必需脂肪酸，有助于言语和注意力。 您的身体无法自行产生 Omega-3 ASA, 您
必须从饮食中获取。
BRT: 补充 Omega-3 脂肪酸可以改善自闭症谱系障碍儿童的多动症、嗜睡症和刻板行为: 一项随机对照
试验的荟葵分析
。 Article: Fish oil capsules help children with speech disorders find their voices
文章: GRBs Biats) LSRAB CHAS
L-Carnosine L-肌肽
L-Carnosine, is a naturally occurring amino acid found in high concentrations in muscle, heart, and brain
tissues. Doctors use it when treating liver disease, Alzheimer’s disease, and cancer. In the study below,
children with autism who were given L-Carnosine showed significant improvements in behavior,
socialization, and communication, as well as increases in language comprehension.
上上-肌肽是一种天然存在的氨基酸，在肌肉、心脏和脑组织中含量很高。医生在治疗肝病、阿尔茨海默病和癌症时
会使用它。在下面的研究中，服用 上-肌肽的自闭症儿童在行为、社交和沟通方面表现出显着改善，并且语言理解
能力也有所提高。
FAS: 左旋肉碱和自闭症: 改善被诊断患有自闭症谱系障碍 (ASD) 的儿童的语言和行为
Creatine 肌酸
Creatine is an amino acid that supplies energy to muscles through the blood. By contrast, Creatinine is a
biological waste formed by the metabolism of creatine and excreted from the body in urine. If creatinine
is low, creatine may be low. According to Dr. Ben Lynch, if you have a child that is low muscle tone, not
gaining weight, is low energy, and has a speech or developmental delay, then check their GAMT SNP. If
they are ++ on this SNP, they may have a creatine deficiency.
2A, AT MRANLATRER. MICE, WESABE CRA eD, Hii bRAHEM IK
Sh. VORA EHR, VAR OSHE. Hee, RORRAAFALASKIK, (EMEDI, Re, HBAS
语或发育迟缓，那么检查他们的 GAMT SNP。如果他们在该 SNP 上为 ++，他们可能患有肌酸缺乏症。
e Find more information about creatine deficiency and its association with autism and speech
delays here
在此处查找有关肌酸缺乏症及其与语言和言语延迟的关系的更多信息
e Learn more from Dr Lynch here
在此处了解有关林奇医生的更多信息
L-Carnitine 左旋肉碱
L-carnitine is an important amino acid that improves mitochondrial function, thereby possibly improving
speech. It is available via prescription or over-the-counter.
左旋肉碱是一种重要的氨基酸，可改善线粒体功能，从而可能改善言语。它可通过处方或非处方药获得。
文章: 研究人员调查了肉碱缺乏症与自闭症之间的可能联系
Ubiquinol (COQ10) 辅酶Q10 (COQ10)
Ubiquinol is the bioavailable form of CoQ10. It helps the mitochondria produce energy and makes ATP,
which your body needs to carry out all of its functions. In the study mentioned below, data results
showed a 21% improvement in verbal communication with supplementation of ubiquinol.
辅酶Q10是辅酶Q10的生物利用形式。它有助于产生能量并产生三磷酸腺苷 (ATP) ，而您的身体需要三磷酸腺苷
(ATP) 来执行所有功能。在下面提到的研究中，数据结果显示，辅酶Q10补充剂使语言交流能力提高了21%。
e Study: Ubiquinol Improves Symptoms in Children with Autism
研究: 辅酶 Q10 可改善自闭症儿童的症状
Sulforaphane 8 hii
Sulforaphane is a sulfur-rich compound found in cruciferous vegetables like broccoli. It is an anti-
inflammatory that has many health benefits. The study cited below showed a 42% increase in verbal
communication on Sulforaphane.
萝卜硫素是一种富含硫的化合物，存在于十字花科蔬菜中，如西兰花。它是一种具有多种健康益处的抗炎剂。 下
面引用的研究表明，芝卜硫素可使语言交流能力提高 42%。
。Study: Sulforaphane treatment of autism spectrum disorder (ASD)
研究: B NARA SAEs hae (ASD)
B6 (P5P) and Magnesium
B6 (P5P) 和镁
B6 is a water-soluble vitamin your body needs to create red blood cells and neurotransmitters (P5P is the
activated form of vitamin B6). Magnesium is an essential mineral that every cell in your body needs to
function. Both magnesium and vitamin B6 play important roles in cognition and mood regulation.
B6 是一种水溶性维生素，身体需要它来制造红细胞和神经递质 (P5P 是维生素 B6 的活性形式) 。镁是一种必需
的矿物质，身体的每个细胞都需要它才能发挥作用。镁和维生素 B6 在认知和情绪调节中都起着重要作用。
。 Study: Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin
研究: 补充镁维生素 BO 的儿童神经行为障碍的改善。儿. 广泛性发育障碍-自闭症
Vitamin D 维生素 D
Many children with autism have a vitamin D deficiency. Testing your child’s vitamin D level is important
because the level should be between 50 and 80. In the study linked below, 1529 patients with ASD, aged
3-18, were tested for Vitamin D deficiency. Vitamin D deficiency or insufficiency was found in
approximately 95% of all patients. Furthermore, levels of vitamin D in kids with ASD ages 11 to 18 years
old were significantly LOWER than those kids younger than 11 years.
许多自闭症儿童患有维生素 D 缺乏症。检测孩子的维生素 D 水平很重要，因为该水平应在 50 到 80 之间。在下
面链接的研究中，对 1529 名 3-18 SAY ASD 患者进行了维生素 D 缺乏症检测。大约 95% 的患者被发现患有维
生素 D 缺乏症或不足。此外，11 至 18 SAY ASD 儿童的维生素 D 水平明显低于 11 岁以下的儿童。
e Study: Vitamin D levels in children and adolescents with autism
研究: 自闭症儿童和青少年的维生素 D 水平
e Vitamin D is an anti-inflammatory.
Iron &
The mineral iron plays an important role in cognitive and motor development. Iron deficiency may
increase the severity of autism symptoms, including a lack of speech. Too much iron can be toxic, so you
should NOT begin iron supplementation unless you're under the care of a physician who is monitoring
levels of both iron and ferritin (iron stores).
矿物质铁在认知和运动发育中起着重要作用。缺铁可能会加重自闭症症状的严重程度，包括缺乏言语。过多的铁
可能有毒，因此，除非您在监测铁和铁蛋白 (铁储备) 水平的医生的照料下，否则您不应开始补充铁。
FAR: 自闭症谱系障碍中的缺铁参数: 临床相关因素和相关因素
Butyrate 丁酸
Butyrate is a short-chain fatty acid. It has been shown to improve mitochondrial function, thereby
possibly improving speech.
丁酸是一种短链脂肪酸。它已被证明可以改善线粒体功能，从而可能改善言语。
凯莉`多夫曼的失用症方案
A combination of phosphatidylcholine, Vitamin E, and Omega 3s has helped many kids with speech. Her
protocol can be found here.
磷脂酰胆碱、维生素E 和 Omega 3 的组合帮助了许多有言语障碍的孩子。她的方案可以在这里找到。
Conclusion 结论
In short, there are many medical issues that can cause or contribute to speech issues in autism. However,
these medical issues cannot be remedied with therapy alone. Therefore, it is important to look at speech
intervention from both a therapeutic and medical approach. Doing so will improve your child’s outcome
and quality of life. After all, when a person feels better, their ability to learn and develop new skills
increases.
简而言之，有很多医学问题会导致或促成自闭症的言语问题。然而，仅靠治疗无法解决这些医学问题。因此，从
治疗和医学两方面考虑言语干预非常重要。这样做将改善您孩子的结果和生活质量。毕竟，当一个人感觉好些
时，他们学习和发展新技能的能力就会提高。
Finally, we understand that navigating speech issues in autism can be difficult. However, it is important to
remember that difficult does NOT mean impossible. Especially when you have support. Please consider
joining our online parent support group or signing up for a TACA parent mentor. Our volunteers do what
they do because they don’t want anyone, including you, to have to travel this journey alone.
最后，我们理解在自闭症中解决言语问题是困难的。然而，重要的是要记住困难并不意味着不可能。特别是当您
有支持时。请考虑加入我们的在线家长支持小组或注册 TACA 家长导师。我们的志愿者之所以做他们做的事情，
是因为他们不希望任何人，包括您，独自踏上这段旅程。
页:
[1]