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StarCare 发表于 2026-5-14 12:56:20

TACA-33 自闭症中的免疫功能异常

本帖最后由 StarCare 于 2026-5-15 16:49 编辑

TACA-33 自闭症中的免疫功能异常
Immune Dysfunction in Autism

原文网址:https://tacanow.org/family-resou ... e-autism-community/

概述

免疫功能异常是自闭症中最常见的共病之一。研究表明,自闭症患者的免疫系统功能与典型发育个体存在差异。本文将讨论自闭症中免疫功能异常的类型、表现和治疗方法。



The bodys immune system defends against infection and protects its own cells. However, research has
shown that the immune system is not working properly in many autism cases. Therefore, immune
dysfunction is a new area of study in autism.

人体的免疫系统防御感染并保护自身细胞。然而,研究表明,在许多自闭症病例
此,免疫功能障碍是自闭症研究的新领域。

,免疫系统功能不正常。

In fact, this 2022 study showed that people with autism could be dealing with upregulated immune genes
leading to brain inflammation. Of the 1275 genes studied, autistic brains had 275 genes that expressed
differently than controls. Interestingly, the autism-related expression pattern most closely resembled
Alzheimer’s and Parkinson's immune gene expression pattern.

实上,这项 2022 年的研究表明,自闭症人士可能正在处理上调的免疫基因,导致大脑炎症。在研究的 1275 个
中,自闭症大脑有 275 个基因的表达方式与对照不同。有趣的是,与自闭症相关的表达模式最接近阿尔茨海
默病和帕金森病的免疫基因表达模式。

i

In addition, this 2023 study showed an altered cytokine profile in adult patients with autism compared to
the control group which may indicate immune dysregulation in a subgroup of adult ASD patients.

此外,这项 2023 AUT, SWRI, SAP AMATISRE Tess, RARER
闭症 (ASD) 患者亚组存在免疫失调。

Lastly, there is new research showing maternal immune dysregulation is a prenatal risk factor for autism
spectrum disorder (ASD). In other words, inflammation and metabolic stress on the pregnant mother can
result in abnormal cytokine (immune system) signaling and autoimmunity.

最后,有新的研究表明,母体免疫失调是自闭症谱系障碍 (ASD) 的产前风险|
和代谢压力可能导致异常的细胞因子 (HERR) 信号和自身免疫。

素。换名话说,孕妇体内的炎症

Butthere is good news. There are treatments and lifestyle changes that can help immune
dysfunction.

但是有好消息。有治疗和生活习惯的改变可以帮助免疫功能障碍。
This article will cover: 本文将涵盖:                                                                                                                        =

。Signs of immune dysfunction
免疫功能障碍的迹象

。Medical issues in autism caused by immune dysfunction

自闭症中由免疫功能失调引起的医疗问题
。Testing for immune dysfunction
检测免疫功能障碍
e Treatment for immune dysfunction
治疗免疫功能障碍

Signs of Immune
Dysfunction

Better with fever
Sick too often
No fevers
No acute illnesses
Losing skills

Behavioral symptoms
of acute illnesses

Signs of Immune Dysfunction

25       = Porons
免疫功能障碍的迹象
There are hints that may point to immune dysfunction in your child. Being observant by journaling can

help detect patterns.
孩子可能存在免疫功能障碍的迹象。通过记录日记进行观察可以帮助发现模式。

Suspect immune dysfunction when your child:

怀疑您的孩子存在免疫功能异常时:

。Has more illnesses than a typical child.
患有比普通儿童更多的疾病。
。Does not mount a fever to fight illnesses.
不发烧来抵抗疾病。
。Does not have typical illness symptoms, but has behavioral issues instead.
不具有典型疾病症状,但出现行为问题。
。Has skill regression. 有技能倒退。
。Has improvement of autism symptoms while fevering (often called the “fever effect”).
热时自闭症症状有所改善 (通常称为"发热效应") 。
。Rarely gets sick, even when other household members are sick.
很少生病,即使其他家庭成员生病时也不例外。

。Has signs of the medical issues listed below.

具有以下列出的医疗问题迹象。
只有一:一一| toon   人
WICUILAL IS55      Ci tll AULISITI    uscU VV

3

3a
cw
> Ww)
o mw

Dysfunction

Primary or Secondary Immunodeficiency
PANDAS / PANS
Autoimmune Encephalitis

Mast Cell Activation

Recurring Acute Infec
| Chronic Infections

Medical Issues in Autism Caused by Immune
Dysfunction

自闭症中由免疫功能异常引起的医疗问题

Immune dysfunction seen in autism will manifest as medical issues. Furthermore, these medical issues
often have behavioral effects alongside other symtpoms. Examples of some of the common medical
issues in autism are listed below.

自闭症中观察到的免疫功能失调将表现为医疗问题。此外,这些医疗问题通常伴随着其他症状,
响。以下列出了自闭症中一些常见医疗问题的例子。

#伴有行为影

Primary or secondary immunodeficiency

原发性或继发性免疫缺陷

Primary immunodeficiency happens when the immune system doesn’t work as it should.

原发性免疫缺陷发生在免疫系统不能正常工作时。

Examples of primary immunodeficiency disorders include:

原发性免疫缺陷病的例子包括:

。Common variable immunodeficiency (CVID)
常见变异免疫缺陷病 (CVID)

。Severe combined immunodeficiency (SCID)
严重联合免疫缺陷病 (SCID)

。Chronic granulomatous disease (CGD)
‘Stes (CGD)

Secondary immunodeficiency disorders happen when an outside source weakens the body, such as a
chemical or infection.

二次免疫缺陷病发生在外部

素削弱身体时,例如化学物质或感染。

Symptoms of primary or secondary immunodeficiency include:

原发性或继发性免疫缺陷的症状包括:

Anemia 贫血

Delayed growth and development
生长发育迟缓

Digestive problems 消化问题
Frequent illness or infections. For example:
频繁生病或感染。例如:

= Pneumonia 肺炎

> Sinus infections 鼻窦炎

> Ear infections 耳部感染

© Strep 链球菌

© Skin infections 皮肤感染

Pediatric Autoimmune Neuropsychiatric Disorders associated with Streptococcal Infections
(PANDAS)

儿童链球菌感染相关自身免疫性神经精神性障碍 (PANDAS)
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)

儿童急性起病神经精神综合征

PANS / PANDAS is largely an autoimmune disorder, resulting from infections or environmental triggers

that cause abnormal activation of the immune system. These infections cause the child to create

antibodies which attack the basal ganglia region of the brain causing a whole host of behaviors.                                          一
However, there are other known causes of PANS as well such as concussions and metabolic issues.

PANS / PANDAS 主要是一种自身免疫性疾病,由感染或环境诱因引起免疫系统异常激活所致。这些感染导致儿童
产生抗体,攻击大脑基底神经节区域,引发一系列行为。然而,PANS 还有其他已知原因,如脑震荡和代谢问
题。

Symptoms include: 症状包括:

。Onset or recurrence of OCD and/or Restrictive eating disorder

onset 或复发 强迫症和/或 限制性饮食障碍
。Also, at least one of the following neuropsychiatric symptoms:
此外,以下至少一种神经精神症状:
© Behavioral/developmental regression
行为/发育倒退
© Deterioration of school performance
学习成绩下降
5 Extreme emotions 极端情绪
> Separation anxiety 分离焦虑
> Sensory/motor abnormalities such as handwriting deterioration
感觉/运动异常,如书写能力下降
© Sleep disturbance (difficulty falling asleep, restless sleep)
exeorrs (eee exo,
睡眠障碍 (ARE, BRRANSZ)
> Urinary symptoms (urgency, frequency, bedwetting)

排尿症状(急迫、频次、夜间遗尿)

Autoimmune Encephalitis (AE)

自身免疫性脑炎 (AE)

Autoimmune encephalitis (AE) occurs when the body’s immune system attacks the brain, causing
inflammation. As a result, the immune system produces substances called antibodies that mistakenly
attack brain cells. While there is still some debate in the medical community, the current criteria needed
for an AE diagnosis is published in this research paper and is also listed below.

自身免疫性脑炎 (AE) 发生在身体的免疫系统攻击大脑,导致炎症。因此,免疫系统产生称为抗体的物质,错误
地攻击脑细胞。尽管在医疗界仍有一些争议,但本研究论文中发表的 AE 诊断所需的标准已列出如下。

Symptoms include: 症状包括:

。Subacute onset (rapid progression of less than 3 months) of:
天性发作 (DF 3 个月的快速进展) 的:
© Working memory deficits 工作记忆缺陷
© Altered mental status “精神状态改变
> Psychiatric symptoms 精神症状
¢ At least 1 of the following criteria:
至少符合以下标准之一:
© New focal CNS findings
新中枢神经系统焦点发现
5 Seizures or EEG abnormalities not explained by a preexisting disorder
疗病发作或无法用现有疾病解释的脑电图异常
5 CSF pleocytosis (white blood cell count of more than 5 cells per mm)

了脑背液多核细胞增多 〈每毫米超过 5 个细胞)
2 VSS ANE > 个名叱/

BYR ae

> MRI suggesting brain swelling (encephalitis)
MRI 提示脑肿胀 〈脑炎)
Other reasons for these symptoms are ruled out.
其他导致这些症状的原因已被排除。
Unlike PANS that causes “flares”, these symptoms continue to get worse rapidly.
与导致"发作'的 PANS Ais], MERKUR,
Please note that AE can present differently in children.
请注意,AE 在儿童中的表现可能不同。

Diagnosing AE in children is based on the combination of a clinical history and supportive diagnostic
testing, which includes but is not dependent on antibody testing.

儿童 AE 的诊断基于临床病史和辅助诊断测试的结合,这些测试包括但不限于抗体检测。

Mast cell activation 肥大细胞活化

When a resting mast cell is stimulated by an allergic reaction, the mast cell releases its contents of
histamine, interleukins, platelet activating factor prostaglandins, proteoglycans, and enzymes. However,
over the next 6-24 hours, other inflammatory molecules are released. Mast cell activation disorders
range from mildly problematic to severe.

当静止的肥大细胞被过敏反应刺激时,肥大细胞会释放其组胺、和白细胞介素、血小板活化因子、前列腺素、蛋白
聚糖和酶。然而,在接下来的 6-24 小时内,还会释放其他炎症分子。肥大细胞活化障碍的范围从轻微问题到

Symptoms include: 症状包括;

。Brain fog 脑雾
Diarrhea 腹泻

Flushing 冲洗
Headaches 头痛

Heart palpitations (4%
Hives 风团

Itching =

Low blood pressure 低血压

Muscle pain 肌肉疼痛

Peripheral neuropathy (numbness, tingling)
周围神经病变 (麻木、刺痛)

。 Shortness of breath 气促
。Skin sensitivity to hygiene products or topicals

皮肤对卫生产品或外用药物的敏感性

Ehlers-Danlos syndrome (EDS) or Hypermobile Ehlers-Danlos syndrome (hEDS)

埃勒斯-当洛斯综合征 (EDS) 或高可动性埃勒斯-当洛斯综合征 (hEDS)

Ehlers-Danlos syndrome (EDS) affects your connective tissues 一 primarily your skin, joints and blood
vessel walls.

埃勒斯-当洛斯综合征 (EDS) 影响您的结缔组织一一主要是您的皮肤、关节和血管壁。

Hypermobile Ehlers-Danlos syndrome (hEDS) is a less severe form of EDS causing joint hypermobility.
This is a result of defects in the collagen protein.

高活动性埃勒斯-当洛斯综合征 (hEDS) 是 EDS 的一种较轻形式,导致关节过度活动。这是胶原蛋|
果。

缺陷的结

Symptoms include: 症状包括;

。Easy bruising Bis
e Flat feet 平足
。 Inflammatory bowel disease
Joint hyper mobility 关节过度活动
e Muscle or bone pain

肌肉或骨痛
。Muscle weakness 肌肉无力
。Stretchy skin 弹性皮肤

Recurring Acute Infections

反复发作的急性感染

Infections can cause inflammation in the body. In addition, when we treat with antibiotics, the bacteria or
virus may hide under biofilms only to resurface often.

aaa炎。此外,当我们使用抗生素治疗时,细菌或病毒可能隐藏在生物膜下,然后经常再次出
Bo

Examples of recurring acute infections are:
急性复发性感染的例子包括:

。Strep 链球菌
> Look for strawberry tongue, red anal ring, peeling fingers/feet, enlarged tonsils/adenoids.
寻找草莓舌、红色肛门环、脱皮的手指/脚趾、肿大的扁桃体/腺体。
。Mycoplasma 支原体
© Look for fatigue 寻找疲劳

Persistent chronic infections
持续慢性感染

When the body does not mount a proper response to an infection or virus, it does not fight off the acute
illness as it should. Consequently, the infection or bacteria is left festering in the body wreaking havoc
on the immune system.

当身体对感染或病毒没有做出适当反应时,它无法像应该的那样抵抗急性疾病。
对免疫系统造成破坏。

此,感染或细菌在体内滋生,

此类慢性感染的例子包括:

*。Lyme and/or Lyme co-infections
莱姆病和/或莱姆病共感染
> Symptoms listed in this TACA article titled “Lyme and Autism”.
症状列在 TACA 文章《莱姆病与自闭症》
。Bartonella 巴顿菌
© Look for swollen glands around the head.
寻找头部周围的肿大淋巴结。
© Additionally, look for unusual streak rash that looks like stretch mark.
此外,寻找类似妊娠纹的不寻常条纹状皮疙。
> Finally, rage is a known symptom of Bartonella.
最后,愤她是巴通体感染已知的一种症状。
。Babesia BH
© Look for unusual sweating at night, fatigue, and nausea.
夜间寻找异常出汗、疲劳和恶心。
。COVID 新冠病毒
> Look for brain fog, dizziness upon standing, and/or extreme fatigue.
寻找大脑模贿、站立时头晕和/或极度疲劳。
e Herpes family infections
单纯疱疹病毒家族感染
© Epstein-Barr virus (EBV) 爱泼斯坦-巴尔病毒 (EBV)
。Look for swollen lymph nodes, extreme fatigue.
寻找肿大的淋巴结,极度疲劳。
5 Cytomegalovirus (CMV) 巨细胞病毒 (CMV)
¢ Look for swollen lymph nodes, fatigue, and nausea.
寻找肿大的淋巴结、疲劳和恶心。
o HHV6 (most common symptom is Roseola)
HHV6 (SF UAEREBERE)
¢ Look for fatigue, abdominal pain, sore throat that comes and goes.
FES, ISA, NAN TCHURIA.
> Herpes Simplex Virus 1& 2
单纯疱痛病毒1型和2 型
。Look for mouth sores/ulcers.
寻找口腔溃疡。
© Varicella (Chickenpox) 7k/& (38/8)
¢ Look for numbness in hands or feet, fatigue, possible random rashes or spots.
寻找手或脚的麻木、疲劳,可能出现的随机皮疙或斑点。

。Parasitic infections 寄生虫感染
> All parasitic infections have different symtpoms.

所有寄生虫感染都有不同的症状。
> Look for low iron and high eosinophils without allergic reactions.
寻找无过敏反应的低铁和高嗜酸性粒细胞。
。Candida overgrowth 念珠菌过度生长
5 Look for Thrush (white tongue)
Seas (AB)

> Additionally, there are many behavioral signs of yeast. Learn more in the TACA article on “Yeast
Overgrowth in Autism”.

此外,还有许多酵母的行为迹象。在 TACA 关于'“自闭症中的酵母过度生长"的文章中了解更多信息。

Testing for
Immune
Dysfunction

Testing for Immune Dysfunction

检测免疫功能障碍

Afull workup of your child is necessary. See the following list of tests that may be run by your
immunologist or functional medicine provider to uncover what the body may be dealing
with. Specifically, the particular tests run will depend on what symptoms are displayed.

对孩子进行全面检查是必要的。请参阅以下由免疫学家或功能医学提供者可能进行的测试列表,以了解身体可能
正在应对的问题。具体进行的测试将取决于所显示的症状。                                                       一

« CBC
Platelets 血小板
e Erythrocyte sedimentation rate (ESR
红细胞沉降率 (ESR)
。C-reactive protein (CRP)
C-反应蛋白 (CRP)
。Oxidative Stress markers
氧化应激标志物
© 80H Deoxyguanosine, Lipid peroxides, Malonodialdehyde
SOHRASEH, mS, ALR
¢ Total immunoglobin profile
BREESE
> IgG and IgG subclasses, IgE, IgA, and IgM
IgG #01 IgG WSS, IgE, IgA 和 IgM
e White Blood Cell Count (WBC)
细胞计数 (WBC)
¢ T lymphocyte panel- CD4/CD8
T 淋巴细胞而板 - CD4/CD8
© ANA 抗核抗体

Vit D level 维生素 D 水于
。 Zinc level (test alongside copper level)

锌水平 (Sikri)
。Testing for specific infections
检测特定感染                                                                                                                               ™
> Both IgM (current infection) and IgG (past infection)
两者均为 1g9M (当前感染) 和 IgG (BHERER)
。S-100B (serum) S-100B (血清)
> Tests blood brain barrier permeability
检测血脑屏障通透性
。Cytokine panels 细胞因子面板
> Quest Diagnostics - Encephalitis antibody evaluation
bean Sara
e Covered by health insurance
涵盖在医疗保险范围内
© Cunningham Panel 坎宁安面板
。 Not covered by insurance                                                                                              ‘
未涵盖在保险范围内
> Mayo Encephalitis Panel 梅奥脑炎小组
se。Covered by insurance but requires a specific draw method
保险覆盖但需要特定的提取方式
。Adults: Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum
成人: I, BSS / RHA 18
¢ Children: PCDES / Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum
儿童: PCDES / 儿童自身免疫性脑炎/中枢神经系统疾病评估,血清

。Cytokine testing such as:

Quest Diagnostics -

细胞因子检测,例如:
> IL-1
Elevated with Candida 升高了念珠菌
© IL-6
« Elevated with PANDAS 升高伴随 PANDAS
> IL-17

e Elevated with PANDAS, Candida
FHSS PANDAS, SEREI
© IL-8
。 Elevated with Clostridia
Fis Seeks
e NLRP.
© Elevated with Candida 升高了念珠菌
。LPS 脂多糖
© Elevated with Gram Negative Bacteria
升高与革兰氏阴性菌相关
> Detects leaky gut 检测漏肠
« D-dimer D-二聚体
5 Looks for protein fragments of blood clots
寻找血栓的蛋白质片段
Nasal swab for MARCoNS
鼻拭子检测 MARCONS
。Celiac panel 肠激酶检测
e Thyroid Peroxidase antibodies
甲状腺过氧化物酶抗体
* NMDA antibodies NMDA 抗体
* GAD65 antibodies GAD65 抗体
。 If necessary, an autoimmune encephalopathy workup via lumbar puncture
如有必要,通过腰椎穿刺进行自身免疫性脑炎的检查

TREATmENT FOR
IMMUNE

Look for Acute Infections

Healthy Diet
DYSFUN CTION                Avoid Environmental
Triggers
Fr                  Address Gut Health

Reduce Inflammation
odulate Immune System

ntimicrobials (if
necessary)

Treatment for Immune Dysfunction
免疫功能障碍的治疗

Effective treatment for immune dysfunction requires a multi-pronged approach. Overall, the goal is to
figure out your child's trigger(s), sensitivities, and clean up the environment.

有效治疗免疫功能障碍需要多管齐下的方法。总体而言,目标是找出您孩子的触发|

清理环境。

Look for acute infections that we may not be able to see. If found, treat.
寻找我们可能看不到的急性感染。如果发现,进行治
e Sinuses, ears, tonsils, adenoids
BSS, BAR, mevea, BRECK
e Urinary tract, bladder, or kidney infection
WRG, BPE Sie
e Skin infection 皮肤感染
* Gut infection 肠道感染
¢ Tooth infection 牙齿感染

Pay attention to Diet 注意饮食

* Mediterranean Diet 地中海饮食

。Anti-inflammatory foods 抗炎食物

Lots of fruits and vegetables
许多水果和蔬菜
Low sugar or no sugar
低糖或无糖
Maximize antioxidants 最大化抗氧化剂
No excitotoxins (MSG, caffeine, food dyes, additives)
兴奋毒素 (味精、咖啡因、食品色素、添加剂)
GMO free 非转其|
Filtered water 过滤水
Foods that are prebiotics
益生菌食品
High fiber diet 高纤维饮食
Spices 香料
Foods that have probiotics (fermented foods)

Adasen

含有益生菌〈发酵食品) 的食物

Diverse diet in order to diversify the gut flora
多样化的饮食以丰富肠道菌群

Avoid Environmental Triggers
避免环境诱因
。Fragrances 香料
。Pollution 污染
Smokers 吸烟者
Chemicals in the air

空气中的化学物质
。Mold in the house or school

RAPES

Address Gut Health 地址肠道健康

e Check for constipation with an x-ray
检查便秘情况,使用 X 光检查
5 Bowel cleanse if needed
如有需要,进行肠道净化
。Use enzymes as needed
根据需要使用酶
> Pancreatic, digestive enzymes
胰腺,消化酶
e Support the liver for proper bile output
支持肝脏正常分泌胆汁
。Address Biofilms 地址生物膜
。Use prebiotics or probiotics depending on stool testing results:
HESS Bast cake Ee:
» Too much Bacteroides, Allistipes, parabacteroides, Prevotella indicates a need for:
RTE. UTE, RTE, SRARUSRARE:
¢ High fiber diet 高纤维饮食

¢ No inulin FER
Not enough Bacteroides, Allistipes, parabacteroides, Prevotella indicates a need for:

细菌短杆菌、拟杆菌、副拟杆菌、普盏沃菌不足表明需要:
Inulin (short-term only)
菊粉 (短期使用)

Animal based protein 动物蛋白

Too much Bacillus, Clostridium, Enterococcus, Lactobacillus, Ruminoccocus indicates a need for:
WSWAMITE A. ER, FLITE, BBR

Lactulose 乳果糖

High Bifido requires berberine

高比非德需要黄连素

High Clostridia requires Carnitine, S. Boulardii, High dose probiotics

高 clostridia 需要肉碱、S. Boulardii、高剂量益生菌

Not enough Bacillus, Clostridium, Enterococcus, Lactobacillus, Ruminoccocus indicates a need for:
Gl, (RE WEE, FTE, BEARER

Inulin 菊粉

Plant based diet 植物性饮食

Resistant starches 抗性淀粉

Lactobacillus Rhamnosus (gg)

鼠李糖乳杆菌 (99)

Bifido Logum 双歧杆菌罗格姆

Supplements to Reduce Inflammation
补充剂以减少炎症
。Resveratrol A228
。Boswellia 乳香
。Curcumin 姜黄素
。Fish Oil (Omega 3 fatty acids)
鱼油 (欧米茄 3 脂肪酸)
Aloe (certified) 芦荟 〈认证)
。Pycnogenol 吡诺辛
。Ashwagandha 阿什瓦甘达

。Berberine 黄连素
。 PEA

Nutrients used for Immunoregulation
SRDS
Zinc (very important) # (非常重要)
e Vitamin A (very important)
维生素 A (非常重要)
e Vitamin D (very important)
维生素 D (非常重要)
5 Blood levels should be between 50-80
血液水平应在 50-80 之间
。lron 铁
e Selenium 7
¢ Molybdenum $8
« Vitamin B1 维生素 B1
© Needed to get sugar into the mitochondria for energy
需要将糖分带入线粒体以获取能量
。B2
。Vitamin B6 维生素 B6
。Folinic acid or SMTHF
叶酸或 5-甲基四氢叶酸
© Never folic acid 从未叶酸
* Vitamin B12 维生素 B12
Vitamin C 维:
Vitamin E 维生素E

Other Anti-inflammatory Treatments
其他抗炎治疗
。 Steroids (short term bursts only)
类国醇 〈仅短期爆发使用)
。IVIG
e Anti-seizure medication such as Lamictal, Depakote, Keppra
TRS, URI, eES. FS
。LDI (Low dose Immunotherapy)
低剂量免疫疗法 (LD)
。Camels milk 骆驼奶

Immune Modulators 免疫调节剂
In autism, the idea is not to boost the immune system, but rather, to modulate it. These products are
known to do that.

自闭症中,目标不是增强免疫系统,而是调节它。这些产品已知可以做到这一点。

。Vitamin D 维生素 D
。IVIG
Helminth Therapy #Ryri&
Low Dose Naltrexone (LDN)
低剂量纳曲酮 (LDN)
Hyperbaric Oxygen treatment
高压氧治疗
。Lauricidin 劳瑞西定
e Amantadine 金刚烷胺

> Tends to be good for lowering OCD

倾向于有助于降低强迫症

Antimicrobials (depending on trigger)
抗菌药物 (根据触发因素)

。Antibiotics 抗生素                                                                                             -
e Antiviral medication (Valtrex)
抗病毒药物 (Valtrex)

。Antiparasitic (Alinia) 抗寄生
。Herbals: 草药:

> Goldenseal 黄连

> Neem 尼姆

5 Berberine SE%

药 (阿立尼

)

© Olive Leaf Extract MUSTER

Conclusion 结论

Immune dysfunction is commonly found in autism. Therefore, if you suspect immune system problems in
your child, it is important to find an open-minded doctor to work with you and test your child

properly. Consequently, the lab results will help guide treatment. Remember that there are often triggers
for immune dysfunction. Finding and then treating those triggers is paramount to improved health.
Coupling that with a protocol to lower overall inflammation will give optimal outcomes.

自闭症中常见免疫功能异常。因此,如果您怀疑您的孩子存在免疫系统问题,找到一位开明的医生与您合作并正
确检查您的孩子非常重要。因此,实验室结果将有助于指导治疗。请记住,免疫功能异常通常有触发因素。找到

治疗这些触发因素对于改善健康至关重要。结合降低整体炎症的方案将带来最佳结果。











免疫功能异常的类型

自身免疫倾向:
- 自身抗体产生增加
- 家族自身免疫病史
- 自身免疫性脑炎风险增加

免疫失调:
- T细胞功能异常
- 细胞因子失衡
- 自然杀伤细胞功能改变

慢性炎症:
- 全身炎症标志物升高
- 神经炎症
- 肠道炎症

免疫缺陷:
- IgG亚类缺乏
- 分泌型IgA缺乏
- 免疫应答能力下降

免疫功能异常的表现

反复感染:
- 耳部感染
- 鼻窦感染
- 肺炎
- 皮肤感染
- 尿路感染

行为症状:
- 感染时行为恶化
- PANS/PANDAS症状
- 炎症相关行为问题

身体症状:
- 自身免疫症状
- 过敏症状
- 慢性疲劳

检测方法

基础免疫检测:
- CBC和分类
- 免疫球蛋白水平(IgG、IgA、IgM、IgE)
- IgG亚类
- T细胞亚群

炎症标志物:
- C反应蛋白(CRP)
- 红细胞沉降率(ESR)
- 细胞因子面板

自身免疫检测:
- 抗核抗体(ANA)
- 甲状腺抗体
- 特异性自身抗体

感染检测:
- 病毒血清学
- 细菌培养
- 莱姆病检测

治疗方法

免疫支持营养素:
- 维生素D:免疫调节
- 锌:免疫支持
- 维生素C:免疫增强
- 硒:免疫支持
- 维生素A:粘膜免疫

抗炎治疗:
- Omega-3脂肪酸
- 姜黄素
- 乳香
- 白藜芦醇

免疫调节:
- 低剂量纳曲酮(LDN)
- IVIG
- 维生素D

治疗感染:
- 抗生素
- 抗病毒药物
- 抗真菌药物
- 抗寄生虫药物

肠道免疫支持:
- 益生菌
- 益生元
- 肠道修复

生活方式干预

饮食:
- 抗炎饮食
- 避免敏感食物
- 支持肠道健康

睡眠:
- 充足睡眠支持免疫
- 规律作息

压力管理:
- 减少压力
- 支持肾上腺

运动:
- 适度运动有益免疫
- 避免过度运动

预防策略

减少感染风险:
- 良好的卫生习惯
- 避免感染源
- 支持免疫

减少炎症:
- 抗炎饮食
- 避免毒素
- 支持排毒

监测:
- 定期检测
- 观察症状变化
- 早期干预

结论

免疫功能异常在自闭症中常见且可治疗。通过适当的检测、免疫支持、抗炎治疗和生活方式干预,可以改善免疫功能并减少相关症状。与了解免疫医学的医生合作,制定个性化的治疗方案。

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